Table 2 Associations between dietary patterns and all-cause and breast cancer-specific mortality.

From: Dietary patterns related to biological mechanisms and survival after breast cancer diagnosis: results from a cohort study

 

HR (95% CI)

p- trend

HR (95% CI)

All-cause mortality

Q1

Q2

Q3

Q4

 

Continuous (1–SD increase)

DRRD

Multivariable modela

1 (ref.)

0.96 (0.86– 1.06)

0.89 (0.79– 0.99)

0.80 (0.70– 0.91)

<0.001

0.93 (0.89–0.97)

Dietary patterns mutually adjustedb

1 (ref.)

0.95 (0.85– 1.06)

0.88 (0.78– 0.99)

0.78 (0.68–0.90)

<0.001

0.92 (0.87– 0.96)

ISD

Multivariable model

1 (ref.)

1.03 (0.91– 1.17)

1.12 (0.98– 1.27)

1.12 (0.96– 1.30)

0.079

1.06 (1.00–1.12)

Dietary patterns mutually adjusted

1 (ref.)

1.01 (0.89– 1.15)

1.07 (0.94–1.22)

1.05 (0.90– 1.22)

0.423

1.06 (1.00– 1.12)

ERDP

Multivariable model

1 (ref.)

1.03 (0.91– 1.16)

0.95 (0.83–1.08)

0.99 (0.86– 1.15)

0.609

0.99 (0.94– 1.05)

Dietary patterns mutually adjusted

1 (ref.)

0.99 (0.88– 1.12)

0.89 (0.78–1.01)

0.92 (0.79– 1.06)

0.100

0.97 (0.92– 1.03)

Breast cancer-specific mortality

      

DRRD

Multivariable model

1 (ref.)

0.99 (0.87– 1.14)

0.96 (0.83– 1.11)

0.89 (0.76– 1.05)

0.167

0.96 (0.91–1.02)

Dietary patterns mutually adjusted

1 (ref.)

0.98 (0.86–1.13)

0.94 (0.81–1.10)

0.87 (0.73–1.04)

0.135

0.96 (0.90– 1.01)

ISD

Multivariable model

1 (ref.)

1.03 (0.88– 1.20)

1.10 (0.94– 1.30)

1.12 (0.93– 1.35)

0.161

1.02 (0.96–1.10)

Dietary patterns mutually adjusted

1 (ref.)

1.01 (0.86– 1.19)

1.08 (0.91– 1.27)

1.09 (0.90–1.32)

0.302

1.02 (0.95–1.10)

ERDP

Multivariable model

1 (ref.)

0.94 (0.81 –1.09)

0.90 (0.76– 1.06)

0.90 (0.75–1.07)

0.192

0.96 (0.90– 1.03)

Dietary patterns mutually adjusted

1 (ref.)

0.92 (0.79– 1.08)

0.86 (0.73– 1.02)

0.86 (0.71– 1.03)

0.070

0.95 (0.89– 1.02)

  1. All models were stratified by country and menopausal status at diagnosis and adjusted for age at diagnosis, attained level of education, physical activity, body mass index, alcohol consumption reported at recruitment, smoking habit and intensity as cigarettes per day at recruitment, ever use of hormone for menopause at diagnosis, cancer stage at diagnosis, cancer grade, and tumour receptor status: ER, PR, HER2.
  2. Ref. Reference, HR hazard ratio, CI confidence interval, DRRD diabetes risk reduction diet score, ISD inflammatory score of diet, ERDP oestrogen-related dietary pattern, Q quartile.
  3. aMultivariable model: Hazard ratios derived from a multivariable Cox regression model where exposure is a dietary pattern without including the other two patterns in the model.
  4. bDietary patterns mutually adjusted: hazard ratios derived from a multivariable Cox regression model where each dietary pattern is further adjusted for the other two dietary patterns.
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