Fig. 6: Cell surface phenotype of cDC1s and cDC2s after phagocytosis of apoptotic or necroptotic TC-1 tumor cells. | Cell Death & Differentiation

Fig. 6: Cell surface phenotype of cDC1s and cDC2s after phagocytosis of apoptotic or necroptotic TC-1 tumor cells.

From: Phagocytosis of necroptotic cells optimizes type 1 conventional dendritic cells for induction of a cytotoxic T-cell response

Fig. 6: Cell surface phenotype of cDC1s and cDC2s after phagocytosis of apoptotic or necroptotic TC-1 tumor cells.The alternative text for this image may have been generated using AI.

The phagocytosis assay was carried out as described in Fig. 5A and cells in the culture were analyzed by flow cytometry. A–D Representative contour plots (left panels) and graphs showing the median fluorescence intensity (MFI) (right panels) of CD80 A and CD86 B in the CTG-negative and CTG positive populations in cDC1s A, B and cDC2s C, D. E, F Representative histograms (left panels) and graphs showing the MFI (right panels) of CCR7 in the CTG- and CTG+ cDC1 E and cDC2 populations F. Each individual value within a graph belongs to an independent experiment. ns, not significant; *P < 0.05; **P < 0.01; one-tailed paired Student’s t-test.

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