Fig. 2: DLEU1 essentially controls various malignant behaviors of breast cancer cells.

MDA-MB-468 and MCF7 cells were either not transfected (control), or stably transfected with shNC, shDLEU1#1, #2, #3, or #4. A DLEU1 level was examined by RT-PCR. B The proliferation of shNC, shDLEU1#2, or shDLEU1#3 cells was examined by MTT assay. C Cell proliferation was examined by colony formation assay (left), with the quantification of colony numbers on the right. The migration (D) and the invasion (E) of indicated cells were examined by Transwell assays (left), with the number of migrated/invaded cells presented on the right. *P < 0.05, **P < 0.01, ***P < 0.001.