Fig. 6: MiR-424-5p inhibitor diminished TRPM2-AS knockdown on endometrial cancer malignant phenotypes. | Cell Death & Disease

Fig. 6: MiR-424-5p inhibitor diminished TRPM2-AS knockdown on endometrial cancer malignant phenotypes.

From: PDIA6, which is regulated by TRPM2-AS/miR-424-5p axis, promotes endometrial cancer progression via TGF-beta pathway

Fig. 6: MiR-424-5p inhibitor diminished TRPM2-AS knockdown on endometrial cancer malignant phenotypes.The alternative text for this image may have been generated using AI.

A, B Colony formation assay and EDU assay were carried to investigate the effect of miR-424-5p inhibitor on cell viability caused by TRPM2-AS downregulation. C Wound healing and Transwell assays were performed to examine the effects of miR-424-5p inhibitor on cell migration and invasion induced by downregulation of TRPM2-AS. D Different expression and analysis of the protein levels of N-cadherin, E-cadherin and c‐MYC were examined by western blotting assay following transfection with shTRPM2-AS and miR-424-5p inhibitor.

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