Fig. 7: PDIA6 overexpression rescued TRPM2-AS knockdown on endometrial cancer malignant phenotypes. | Cell Death & Disease

Fig. 7: PDIA6 overexpression rescued TRPM2-AS knockdown on endometrial cancer malignant phenotypes.

From: PDIA6, which is regulated by TRPM2-AS/miR-424-5p axis, promotes endometrial cancer progression via TGF-beta pathway

Fig. 7: PDIA6 overexpression rescued TRPM2-AS knockdown on endometrial cancer malignant phenotypes.The alternative text for this image may have been generated using AI.

A, B Cell viability were detected by CCK8 and colony formation assays while Ishikawa and AN3CA cells were transfected with shTRPM2-AS and PDIA6-OE. C, D Cell motility were tested by Transwell and wound healing assays while Ishikawa and AN3CA cells were transfected with shTRPM2-AS and PDIA6-OE. E KEGG pathway analysis was performed in TRPM2-AS knockdown and control groups based on GSE40687. F, G Protein levels and analysis of PDIA6, TGFBR1, p-Smad2, Smad2, N-cadherin, E-cadherin and c‐MYC expression under different treatments in Ishikawa and AN3CA cells.

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