Fig. 4: Effect of C4BPA on 2D myogenic differentiation. | Cell Death & Disease

Fig. 4: Effect of C4BPA on 2D myogenic differentiation.

From: Impact of C4BPA on Muscle progenitor cell differentiation: insights for Duchenne muscular dystrophy treatment

Fig. 4: Effect of C4BPA on 2D myogenic differentiation.The alternative text for this image may have been generated using AI.

A Timeline scheme of the differentiation of myoblasts with C4BPA treatment. B Bar plot showing the % area of myotubes and the ratio of nuclei/myotube of untreated and treated myoblasts with C4BPA after the differentiation process. C Myotube size graph and fiber size frequency in untreated and treated myoblasts with C4BPA after the differentiation process. D Bar plot showing the proliferation data after 24, 48 and 72 h. E Graphs showing different migratory parameters (mean-speed, median speed, total distance, linearity of forward progression and trajectory path of myoblasts after 72 h in culture. F Relative expression genes analysed after the differentiation process in non-treated and C4BPA-treated myoblasts. Data are represented as the mean of three replicates ± standard error of the mean. Results were statistically analysed using Mann-Whitney U. Statistical significance was set at P < 0.05. **P < 0.01; ***P < 0.001.

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