Fig. 1: RIPK1 was activated in the COVID-19 lungs.
From: SARS-CoV-2 promotes RIPK1 activation to facilitate viral propagation
a IHC staining of p-S166 RIPK1 in the lungs of a COVID-19 patient (middle and right) and an age-matched control (left). Scale bars, 1 inch. The enlarged image (right) shows the nuclear morphology of p-S166 RIPK1+ cells. b Activated RIPK1 in the bronchial ciliated epithelial cells of patients with severe COVID-19. IHC staining of viral nucleocapsid protein (NP) and p-S166 RIPK1 in the bronchial region of the COVID-19 patient and control was shown. The lower row shows the enlarged images of specified areas above. Scale bars, 100 μm. c IHC staining of c-casp3 in the lungs of patients with severe COVID-19 (bottom) and control (top). Scale bars, 20 μm.
