Table 1 Clinical, biochemical, and nutritional characteristics in HFI patients and healthy controls.

From: Correction: Vitamin C and folate status in hereditary fructose intolerance

 

Healthy controls

HFI patients

p value

n

32

32

 

Male/female, n/n

13/19

12/20

0.798

Age, years

16.0 [2.1–61.3]

14.6 [5.5–63.5]

0.961

Weight, kg

50.5 ± 15.3

47.2 ± 15.6

0.401

BMI, kg/m2

20.2 ± 3.2

19.0 ± 3.1

0.710

Plasma vitamin C (µmol/L)

45.1 [10.2–129.5]

49.4 [5.7–138.0]

0.895

Serum folate (nmol/L)

21.5 [12.7–48.7]

24.7 [6.1–54.4]

0.619

Vitamin C hypovitaminosis/deficiency (n; %)

2; 6.3%

7; 21.9%

0.148

Vitamin C deficiency (n; %)

1; 3.1%

5; 15.6%

0.196

Folate deficiency (n; %)

0

1; 3.1%

1.000

Dietary intake

n

28

30

 

Vegetable fiber (g/day)

15.9 [9.4–59.7]

12.1 [6.1–21.4]

0.006

Vitamin C (mg/day)

107.0 [42.8–346.6]

23.8 [6.4–76.1]

<0.001

Folate (µg/day)

202.2 [115.8–524.2]

183.5 [78.6–304.3]

0.027

  1. Continuous variables are represented as mean ± standard deviation or as median [minimum–maximum], depending on data distribution. Significant p values are marked in bold. Body mass index (BMI). Vitamin C hypovitaminosis/deficiency: circulating vitamin C levels ≤23 µmol/L. Vitamin C deficiency: circulating vitamin C levels ≤11 µmol/L.
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