Fig. 3
From: Increased AT1 receptor expression mediates vasoconstriction leading to hypertension in Snx1−/− mice
Enhanced reactivity of mesenteric arteries to Ang II in Snx1−/− mice. a Phenylephrine (PHE)-induced contractions of mouse mesenteric arteries were not changed in Snx1−/− mice; there was no significant difference between WT and Snx1−/− mice (n = 5). b Sodium nitroprusside (SNP)-induced relaxation of mouse mesenteric arteries was not remarkably changed in Snx1−/− mice (n = 5). c Ang II-induced contractions of mouse mesenteric arteries were increased in Snx1−/− mice (*P < 0.05 vs. WT, n = 5)
