Fig. 2
PMIF inhibits Tfh cell development. BALB/cJ mice were infected with 106 PbAWT or PbAmif− iRBCs. On days 6 and 15 after infection, splenocytes were isolated and Tfh cells assessed. a–c Representative plots and absolute numbers of Tfh and pre-Tfh cells in the two groups of mice. Results are from three separate experiments. Bars represent the mean of 12 mice ± SD (*p < 0.05, **p < 0.001 by Mann–Whitney test). d Representative plots and absolute number of CD4+CD62L−Bcl-6hi cells at day 6 after infection, and e expression of transcription factor T-bet in CD4+Bcl-6hi cells. Results are from three separate experiments. Bars represent the mean of 12 mice ± SD; *p < 0.05, **p < 0.001 by Mann–Whitney test
