Fig. 4 | Nature Communications

Fig. 4

From: Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and function

Fig. 4The alternative text for this image may have been generated using AI.

HSPC-pDCs and blood pDCs exhibit shared transcriptomic pathways. a Top 10 biological processes enriched in the set of differentially expressed genes and their associated P values for blood pDCs (black) and IFN-primed HSPC-pDC (gray) after 24 h stimulation with a TLR7 agonist. b Heat map (z-score) of both activated and inhibited upstream regulator genes within the top biological process corresponding to panel (a). c Illustration of regulated genes within the TLR7 pathway of after stimulation of blood pDCs and HSCP-pDC, respectively

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