Fig. 3: Third-generation cephalosporin and colistin resistance profiles differ by lineages and are associated with different plasmids.
From: Evolutionary dynamics of multidrug resistant Salmonella enterica serovar 4,[5],12:i:- in Australia
A AMR genes mediating resistance to third-generation cephalosporins (3GCs) and colistin was detected in the 309 isolates stratified by lineage membership. The * indicates a close but not exact sequence match. Rarefaction curves of the diversity in the unique AMR gene combinations for each lineage are shown to the right. B Regions encoding AMR in plasmids resolved from long-read data for common AMR profiles that mediate resistance to third-generation cephalosporins and /or colistin in the three lineages. C The plasmid STs in the genomes are shown by lineage membership for the top three plasmid replicons detected from the initial plasmid screen. The * indicates a close but not exact sequence match. Rarefaction curves of the diversity in the unique plasmid replicon combinations for each lineage are shown to the right. AMR antimicrobial resistance.
