Table 1 Brain N-glycans.

From: Mammalian brain glycoproteins exhibit diminished glycan complexity compared to other tissues

Glycan Category

Cortex

Hippocampus

Striatum

Cerebellum

F-value

p-value

Paucimannose

3.1 ± 0.2

2.6 ± 0.3

2.6 ± 0.3

1.2 ± 0.1

13.23

0.00005

High-mannose

62.6 ± 1.3

60.8 ± 1.8

60.8 ± 0.6

61.1 ± 1.8

0.32

0.81

Mono-antennary

19.0 ± 0.8

19.2 ± 0.7

18.9 ± 0.4

13.0 ± 0.6

23.39

0.000001

Bi-antennary

13.6 ± 0.9

15.5 ± 1.2

15.4 ± 0.3

21.7 ± 0.9

15.68

0.00002

Tri-antennary

1.7 ± 0.2

1.7 ± 0.3

1.9 ± 0.2

2.6 ± 0.4

2.46

0.09

Tetra-antennary

0.14 ± 0.04

0.18 ± 0.05

0.28 ± 0.07

0.32 ± 0.08

1.69

0.2

Hybrid

5.5 ± 0.2

6.3 ± 0.2

6.7 ± 0.4

8.3 ± 0.4

13.34

0.00005

Bisected

30.3 ± 1.1

32.1 ± 1.5

32.3 ± 0.5

34.4 ± 1.5

1.31

0.3

Galactose

13.5 ± 0.6

12.8 ± 1.2

14.1 ± 0.6

14.1 ± 1.3

0.4

0.76

Fucose

34.7 ± 1.3

36.2 ± 1.9

36.3 ± 0.6

35.3 ± 1.8

0.29

0.83

NeuAc

1.9 ± 0.5

2.3 ± 0.5

2.5 ± 0.6

2.9 ± 0.3

0.8

0.51

NeuGc

0

0

0

0

–

–

  1. Categorical analysis of N-glycans highlighted regional differences in the brain. Data from male mice, presented as mean percent abundance +/− SEM for each category. Significant F- and p-values are indicated in bold, df = (3,20), Fcrit = 3.098, n = 6 per region. Source data are provided as a Source Data file.
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