Fig. 2: Mechanisms of cellular uptake of SPION-based nanovaccines in BMDCs.
From: A nanovaccine for immune activation and prophylactic protection of atherosclerosis in mouse models
a Representative confocal images of BMDCs treated with anti-CD16/32 antibody, fucoidan, mannan, or amiloride incubated with SP-D, SP-D1P1, SP-D1 + P1, and SP-P for 4 h. CpG-ODN was Quasar 670-labeled (red) and p210 was FITC-tagged (green). Nuclei were stained with Hoechst 33342 (blue). b Statistical analysis of the fluorescent intensities after different treatments. n = 5 individual experiments and data are presented as mean ± SD. One-way ANOVA with Dunnett’s post hoc test used to determine significance versus the untreated group. Statistically significant p values are reported; ns mean no significance. Source data are provided as a Source Data file.
