Fig. 3: Details of the AmVg structure.
a, b Unmodelled partial lipid densities in the interior and at the edge of the lipid binding cavity contoured at 7σ. c Phospholipid head group identified at the edge of the lipid binding cavity contoured at 7σ. d Glycosylation at N296. The quality of the density allows the identification of the N-acetyl groups of the first two N-acetylglucosamine units and the identification of up to three more mannose units at lower contour levels. Density shown for the higher-resolution cleavage product of AmVg contoured at 1σ. e Solvent-facing view of the a-helical domain with the side chains of basic amino acids coloured in blue, which have been associated with the ability of Vg to bind membranes21.
