Fig. 3: ProtacID can distinguish between BAF complex variants. | Nature Communications

Fig. 3: ProtacID can distinguish between BAF complex variants.

From: Characterization of PROTAC specificity and endogenous protein interactomes using ProtacID

Fig. 3: ProtacID can distinguish between BAF complex variants.The alternative text for this image may have been generated using AI.

Five different BAF PROTACs were subjected to ProtacID analysis across three different human cell lines (293, 697, and HAP1), as indicated. AU-24118 (blue font) is a CRBN-recruiting PROTAC; all others are VHL-recruiting PROTACs. green—high confidence (BFDR ≤ 0.01) protein identification. white—not identified. Proteins grouped according to BAF variant, as in Fig. 2.

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