Fig. 4: Copy number profiles show distinct genetic alterations in NEN of different organ sites and indicate heterogeneous alterations in hepatic NEN. | Nature Communications

Fig. 4: Copy number profiles show distinct genetic alterations in NEN of different organ sites and indicate heterogeneous alterations in hepatic NEN.

From: DNA methylation patterns facilitate tracing the origin of neuroendocrine neoplasms

Fig. 4: Copy number profiles show distinct genetic alterations in NEN of different organ sites and indicate heterogeneous alterations in hepatic NEN.The alternative text for this image may have been generated using AI.

A NEN of the pancreas (N = 25), B liver metastasis of pancreatic NEN (N = 7), C NEN of the ileum (N = 18), D liver metastasis of ileal NEN (N = 9), E pulmonary small-cell NEC (SCNEC) (N = 14) and F liver metastasis of pulmonary NEN (N = 3). The relative frequency of observed gains (green) and losses (red) are depicted above and below the horizontal line, respectively.

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