Fig. 6: Premature osteoblasts with BMP signaling are spatially modified from the tip to the lateral protrusions of the first dorsal-fin spiny ray in Stephanolepis cirrhifer. | Nature Communications

Fig. 6: Premature osteoblasts with BMP signaling are spatially modified from the tip to the lateral protrusions of the first dorsal-fin spiny ray in Stephanolepis cirrhifer.

From: Actinotrichia-independent developmental mechanisms of spiny rays facilitate the morphological diversification of Acanthomorpha fish fins

Fig. 6: Premature osteoblasts with BMP signaling are spatially modified from the tip to the lateral protrusions of the first dorsal-fin spiny ray in Stephanolepis cirrhifer.The alternative text for this image may have been generated using AI.

a Lateral view of a larva, and a micro-CT scan of the skeleton (n = 2). b Magnified CT image of the dorsal spine. c Distributions of Runx2-positive cells (green) and pSmad1/5/9-positive cells (magenta) in the dorsal spine, stained by immunohistochemistry with DAPI (white) (n = 3). Upper left inset shows a magnified view of the dorsal spine region. Yellow arrow heads show examples of pSmad1/5/9 and Runx2-positive cells. Dorsal-spine bones are outlined in orange. All panels except the left-most panel represent magnified views of the area enclosed by the yellow dashed box in the left-most panel. The left-most picture is a confocal Z-stack image, and the others are optical sections obtained by confocal microscopy.

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