Fig. 1: Representative images of IHC nuclear staining of METTL3, METTL14 and CBLL1 and distribution of H-scores in breast cancer tissue microarrays (TMAs). | npj Breast Cancer

Fig. 1: Representative images of IHC nuclear staining of METTL3, METTL14 and CBLL1 and distribution of H-scores in breast cancer tissue microarrays (TMAs).

From: Functional and clinical significance of the RNA m6A methyltransferase complex in breast cancer

Fig. 1: Representative images of IHC nuclear staining of METTL3, METTL14 and CBLL1 and distribution of H-scores in breast cancer tissue microarrays (TMAs).The alternative text for this image may have been generated using AI.

Representative photomicrographs of (A) low and (D) high level METTL3 expression; (B) low and (E) high level METTL14 expression; and (C) low and (F) high level CBLL1 expression. H-scores assigned to intact cores with tumour coverage >10%. Distribution of H-scores with red line denoting median: (G) METTL3, median H-score 105 (n = 2132); (H) METTL14, median H-score 120 (n = 2321), and (I) CBLL1, median H-score 70 (n = 1524).

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