Fig. 7: Amino acid alterations in the post-mortem superior frontal gyrus of Alzheimer’s disease patients relative to controls. | npj Parkinson's Disease

Fig. 7: Amino acid alterations in the post-mortem superior frontal gyrus of Alzheimer’s disease patients relative to controls.

From: Ultra-performance liquid chromatography–mass spectrometry analysis of post-mortem brain tissue reveals specific amino acid profile dysregulation in Parkinson’s disease and Alzheimer’s disease patients

Fig. 7: Amino acid alterations in the post-mortem superior frontal gyrus of Alzheimer’s disease patients relative to controls.The alternative text for this image may have been generated using AI.

A Heatmap showing standardized amino acid concentrations (z-score) across AD (n = 10) and Ctrl (n = 10) groups. Rows represent individual amino acids and columns represent individual biological samples, highlighting the variation in amino acid levels. B Robust volcano plot for the AD vs. Ctrl, reporting log₂(FC) and –log₁₀(p-value) and identifying five significantly altered amino acids. C Boxplots depicting the amino acids significantly upregulated in AD relative to Ctrl. Ctrl control, AD Alzheimer’s disease, SFG superior frontal gyrus.

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