Fig. 4: Changes in antibody quality between week 50 and 85. | npj Vaccines

Fig. 4: Changes in antibody quality between week 50 and 85.

From: Functional antibody signatures following therapeutic immunization in Simian and Human immunodeficiency virus infection

Fig. 4: Changes in antibody quality between week 50 and 85.The alternative text for this image may have been generated using AI.

Serum Fcγ-R binding and antibody functions at week 50 and week 85 in animals that had received the therapeutic vaccine versus animals that only received PGT121 or placebo. Serum Fcγ-R binding (A) and functions (B) were corrected for the animals Mos-1 gp140-specific total IgG titer (as determined by Luminex) MFI, mean fluorescence intensity. Asterisks indicate statistically significant differences between the groups in the univariate test after correction for multiple comparison (*, P ≤ 0.05; **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001).

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