Fig. 7: Kinetics of Fcγ-R binding and functional antibody response following therapeutic vaccination in the HTX1002 study. | npj Vaccines

Fig. 7: Kinetics of Fcγ-R binding and functional antibody response following therapeutic vaccination in the HTX1002 study.

From: Functional antibody signatures following therapeutic immunization in Simian and Human immunodeficiency virus infection

Fig. 7: Kinetics of Fcγ-R binding and functional antibody response following therapeutic vaccination in the HTX1002 study.The alternative text for this image may have been generated using AI.

A Radar plot representation of the Z-scored Fcγ-R (2 A, 2B, 3 A, 3B) and Fcα-R (AR) binding activity of Mos-1 Env-specific antibody responses throughout the study. B Fold change (to baseline – week 0) functional response levels for Mos-1 Env-specific ADCD, ADCP, ADNP and ADNKA (as determined by CD107a expression or Mip-1β or IFNγ secretion) throughout the study. The different study arms are color-coded. The vertical dotted lines represent the timepoints of vaccine/placebo administration.

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