Extended Data Fig. 3: Temperature rise at the focal point for 10-min ultrasound stimulation.

The maximal acoustic pressure was used for this simulation. Top, temperature rise after 10 min of ultrasound stimulation with a tension of 55 V and pulse duration of 250 µs with a pulse repetition frequency of 4 Hz. The temperature reaches a constant value 5 min after the beginning of stimulation. Bottom, zoom on the first 20s of the top graph.