A chemically modular amino acid-based ionizable lipid platform advances intratracheal lipid nanoparticle-mediated delivery of RNA base editors to airway epithelia and corrects genetic mutation in cystic fibrosis.
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Y.D. is a co-founder and holds equity in Immunanoengineering Therapeutics. D.C. declares no competing interests.
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Cao, D., Dong, Y. Delivering base editors to the lungs. Nat. Mater. (2026). https://doi.org/10.1038/s41563-026-02602-w
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DOI: https://doi.org/10.1038/s41563-026-02602-w