Extended Data Fig. 6: Amino-acid sequences of non-redundant clones isolated during the RBD affinity-maturation process.
From: SARS-CoV-2 variant prediction and antiviral drug design are enabled by RBD in vitro evolution

Rare/transient mutations are in light blue. Important changes are highlighted in dark blue. Except the stabilizing mutation I358F, no additional mutations were identified outside the mutagenized region AA442 – 528.