Extended Data Fig. 5: B cell infiltration of STS is the key factor associated with overall survival.
From: B cells are associated with survival and immunotherapy response in sarcoma
This figure refers to TCGA SARC and GSE21050 pooled cohorts (n = 496). a, Overall survival of patients with STS according to MCP-counter scores for cytotoxic lymphocytes. b, Overall survival of patients based on the infiltration level of their tumours by B lineage cells and cytotoxic lymphocytes. c–e, Overall survival of patients based on degree of tumour infiltration by B lineage cells and expression of PDCD1 (c), CD274 (d) and FOXP3 (e). The analyses were performed with the Kaplan–Meier estimates and two-sided log-rank tests. Tumours were considered high for expression of PDCD1, CD274 and FOXP3 if their expression was above median, and high for B lineage and cytotoxic lymphocytes if the MCP-counter score was above the third quartile.
