Extended Data Fig. 6: Variation in syllable amplitude does not account for the dopamine response.
From: Natural behaviour is learned through dopamine-mediated reinforcement
a, Mean amplitude across all renditions on each day of development (day 61−100) for an example syllable, normalized to the average adult (day > 90) amplitude of that syllable. b, Plotted similarly to a but averaged across all (n = 25) syllables (shading, ±s.e.m.). c, Correlation of the ΔF/F signal with syllable amplitude (see Methods) across development (day 61−100) for an example syllable (black line, best fit line; n.s., p > 0.05, not significant, Pearson linear correlation coefficient). d, Pearson linear correlation coefficient between syllable amplitude and the ΔF/F signal for all syllables (open circles, p > 0.05, not significant; filled circles, p < 0.05, Pearson linear correlation coefficient with Holm–Bonferroni correction57). e,f, Syllable-averaged (n = 25) ΔF/F signals for 10% closest (blue) and 10% furthest (red) relative distance before (e, reproduced from Fig. 2e) and after (f) normalization (see Methods) by syllable amplitude (shading, ± s.e.m). g,h, Scatter plot of averaged ΔF/F signals for all n = 25 syllables for closer (g) and further (h) relative distance comparing not normalized (left) and amplitude-normalized (right) renditions (n.s. P > 0.05, not significant, paired t-test; black bars, mean ± s.d.).
