Fig. 1: A multiomic, multi-organ atlas of human development. | Nature

Fig. 1: A multiomic, multi-organ atlas of human development.

From: Multiomics and deep learning dissect regulatory syntax in human development

Fig. 1: A multiomic, multi-organ atlas of human development.The alternative text for this image may have been generated using AI.

a, HDMA dataset overview and sample size distribution by organ. b, Sample metadata and quality control metrics for RNA-sequencing and ATAC–seq modalities, with samples ranging from post-conception weeks (PCW) 10–23. The number of biologically independent samples per organ is shown in a. PCD, post-conception days. c, Key marker gene expression and transcription factor motif chromVAR deviation z-score for 203 hierarchically clustered cell types. TF, transcription factor. d, An example of different levels of cell annotation for endothelial cells. AG, adrenal gland; BR, brain; EY, eye; HT, heart; LI, liver; LU, lung; MU, muscle; SK, skin; SP, spleen; ST, stomach/oesophagus.

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