Extended Data Fig. 3: Functionality of ILC subsets. | Nature Immunology

Extended Data Fig. 3: Functionality of ILC subsets.

From: Spatial and functional diversity of innate lymphoid cells in the human female genital tract may contribute to antiviral responses to HIV

Extended Data Fig. 3: Functionality of ILC subsets.The alternative text for this image may have been generated using AI.

(a) Contour plots depicting IFN-y expression in CD103+ (left) and CD103- (right) ILC1s. (b) Contour plots of IFN-y expression in CD161+ and CD161- ILC1s. (c) Contour plots of IL-22 expression in the three distinct ILC3 subsets, CCR6 + CD103-, CCR6 + CD103+, and CCR6-. (d) Contour plot of IL-22 expression in CD161+ and CD161- ILC3s. (e) Contour plot of CD107a expression in three ILC3 subsets and ILC1s. (f) Lack of correlation between percentage of IFN-y + ILC1s and IL-22 + ILC3s (top) (n = 32 tissues); endometrial CD107a + ILC3s and IL-22 + ILC3s (middle) (n = 11 tissues); and endometrial CD107a + ILC3s and IFN-y + ILC1s (bottom) (n = 11 tissues). Each dot represents one patient with both values. Spearman rank test (two-sided) for all correlations.

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