Extended Data Fig. 7: Single-cell sequencing from ZymoBIOMICS preserved human fecal microbiome results in under-representation of gram negative taxa.
From: Massively parallel single-cell sequencing of diverse microbial populations
Comparison of relative abundance of the major taxa (>0.1% abundance by 16S profiling) between standard 16S profiling and DoTA-seq of the ZymoBIOMICS human fecal microbiome standard. Since this sample was preserved in DNA/RNA shield which prematurely lyses many types of cells (see Supplementary Fig. 9), many taxa are missing or under-represented in DoTA-seq compared to 16S profiling.
