Extended Data Fig. 4: Arg1+microglia co-localize with CX3CR1-GFP but not with CD206 in P10 mouse brains. | Nature Neuroscience

Extended Data Fig. 4: Arg1+microglia co-localize with CX3CR1-GFP but not with CD206 in P10 mouse brains.

From: ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain

Extended Data Fig. 4: Arg1+microglia co-localize with CX3CR1-GFP but not with CD206 in P10 mouse brains.The alternative text for this image may have been generated using AI.

a, CX3CR1-GFP+/ARG1 + microglia (arrows) coexist with CX3CR1-GFP+/ARG1−microglia (arrowheads) in P10 BF/vStr (representative image from 3 female animals). b, ARG1-positive cells around the ventricles (triple arrows) are not CX3CR1-GFP-positive (see also Extended Data Fig. 1) (representative image from 3 female animals). c, Arg1+microglia do not express the perivascular macrophage marker CD206 (arrows), while perivascular macrophages in this brain area express ARG1 (arrowheads). Note that Arg1+microglia are always ramified, while perivascular macrophages are amoeboid (representative image from 3 female animals). Scale bars, x = 50 μm, z = 10 and 8.5 μm (for a and c, respectively). Yellow squares indicate location of the corresponding images on their left; grey lines indicate the BF/vStr region.

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