Figure 5

TLR4 is required for LLC tumor-induced elevation of circulating catabolic cytokines in mice. Sera collected from mice described in Fig. 3 on day 21 of LLC tumor implant were analyzed for catabolic cytokines TNFα, IL-6 and IL-1β by multiplex immunoassay (Bio-Rad). Data was analyzed by ANOVA. *Denotes a difference (P < 0.05).