Figure 3

Citric acid cycle metabolite level and metabolite ratio analyses upon OR, GR and OGR. Metabolite ratios are indicated by boxes and each box represents a different treatment group (from left to right OR, GR and OGR). Significant metabolite ratio differences are illustrated in pink (increased ratio), blue (decreased ratio) and gray (unchanged ratio). Significant metabolite ratios were calculated by Student’s t-test (compare Fig. S4). Significant metabolite levels were calculated by SAM: *FDR ≤ 0.05; **FDR ≤ 0.01; ***FDR ≤ 0.001. N = 5 per group.