Figure 4

Validation of kinome analysis data was performed using Western blotting (a). The full-length blots are presented in Supplementary Fig. 2S. Cells treated with 10 µM anisomycin (Aniso) were used as a positive control. Cytotoxic effects of MomC and JNK1/2 inhibitor SP600125 alone and in combination (effect = 0 corresponds to 100% cell viability; effect = 1 corresponds to 0% cell viability) (b). Combinational index (CI) values calculated using Chou–Talalay method (c, d).