Table 2 Liver function parameters in EAC-bearing mice after treatment with amygdalin and/or sorafenib.

From: Amygdalin potentiates the anti-cancer effect of Sorafenib on Ehrlich ascites carcinoma and ameliorates the associated liver damage

Group

ALT (U/L)

AST (U/L)

Albumin (g/dL)

Total protein (g/dL)

GGT (U/L)

Cnt

44.75 ± 1.26e,f

59.50 ± 3.87f

4.34 ± 0.15a

6.12 ± 0.18a

19.75 ± 2.01e

Amy

48.25 ± 1.93e

62.75 ± 2.21f

3.67 ± 0.11b

5.15 ± 0.20d

22.00 ± 2.41e

SorIP

56.08 ± 1.58d

67.00 ± 2.73e,f

3.62 ± 0.16b

6.23 ± 0.22a

35.50 ± 2.75c,d

SorOS

54.21 ± 1.35d

69.21 ± 2.13e

3.40 ± 0.09b

5.37 ± 0.17b,d

33.75 ± 2.75d

Amy + SorIP

54.03 ± 1.84d

64.73 ± 2.28a

4.14 ± 0.13a

6.05 ± 0.19a

31.25 ± 3.25d

Amy + SorOS

57.50 ± 2.21d

77.50 ± 3.21d

3.62 ± 0.12b

5.50 ± 0.11b

38.00 ± 3.13c

EAC

86.47 ± 3.51a

165.0 ± 6.72a

2.35 ± 0.09d

4.17 ± 0.23e

154.37 ± 9.21a

EAC + Amy

75.61 ± 3.15b

103.8 ± 5.40b

3.13 ± 0.24b

5.65 ± 0.14b

99.50 ± 7.46b

EAC + SorIP

50.00 ± 2.38d,e

74.00 ± 3.80d,e

3.25 ± 0.11b

5.70 ± 0.16b

33.00 ± 2.13d

EAC + SorOS

66.50 ± 2.49c

88.00 ± 4.41c

3.07 ± 0.15b

5.97 ± 0.24a,b

46.25 ± 2.80c

EAC + Amy + SorIP

39.37 ± 1.48f

48.75 ± 2.15g

3.45 ± 0.13b

6.47 ± 0.17a

39.75 ± 2.13c

EAC + Amy + SorOS

50.25 ± 2.38d,e

75.75 ± 3.59d

3.20 ± 0.11b

5.73 ± 0.17b

34.30 ± 2.34c,d

  1. Data were presented as means ± SEM. Small (a–e) letters showed the marked change at P ≤ 0.05. The significant were expressed by dissimilar letters in the same column.