Figure 3
From: Bioinspired gelatin based sticky hydrogel for diverse surfaces in burn wound care
Mathematical modelling for transdermal drug delivery system: Time-dependent evaluation of salicylic acid release from GbH: (a) graphical illustration of spectrophotometric analysis of controlled drug release profile of patch-A and -B for salicylic acid; (b) illustration of agar well diffusion test for controlled drug release profile of patch-A and -B; (c) graphical illustration of controlled drug release profile of patch-A and -B for salicylic acid agar well diffusion test. Mathematical model representation of drug release from GbH: (d) zero-order, (e) first-order and (f) Higuchian release kinetics. Agar diffusion of GbH: (g.A) UV-sterile GbH performance against E.coli; (g.B) Control plate of UV-sterile GbH performance against E.coli; (g.C) UV-sterile GbH performance against S. aureus; (g.D) Control plate of UV-sterile GbH performance against S. aureus; (g.E) Non-sterile GbH performance against E.coli; (g.F) Control plate of non-sterile GbH performance against E.coli; (g.G) Non-sterile GbH performance against S. aureus; (g.H) Control plate of non-sterile GbH performance against S. aureus; (g.I) UV-sterile GbH performance against C. albicans; (g.J) Control plate of UV-sterile GbH performance against C. albicans; (g.K) Non-sterile GbH performance against C. albicans and (g.L) Control plate of non-sterile GbH performance against C. albicans. (h) illustrate agar overlay performance of GbH where E, S and CA denote E. coli, S. aureus and C. albicans, respectively; C denotes Control plate; C(H) denotes positive control GbH; D(H) denotes test drug-loaded GbH. (i) illustrates patch agar performance of GbH where D1, D2 and D3 are Day 1, 2 and 3, respectively; E, S and CA denote E. coli, S. aureus and C. albicans, respectively; C denotes Cotton patch; D(C) denotes drug-loaded cotton patch; H denotes GbH and D(H) denotes drug-loaded GbH.
