Table 3 Pregnancy outcomes of the cohort.

From: Prevalence of pre-eclampsia and adverse pregnancy outcomes in women with pre-existing cardiomyopathy: a multi-centre retrospective cohort study

Pregnancy outcome

DCM (n = 156)

All (n = 282)

Gestation at delivery* (completed weeks)

38 (27—42)

38 (22—42)

Delivery < 37 weeks

43/152 (28.3%)

73/278 (27.3%)

Delivery < 34 weeks

12/152 (7.9%)

30/278 (10.8%)

Iatrogenic delivery < 34 weeks

11/152 (7.2%)

21/276 (7.6%)

Female sex

49/107 (45.8%)

118/233 (50.6%)

Mode of delivery

Emergency C-section

21/147 (13.4%)

37/273 (13.6%)

Elective C-section

44/147 (29.9%)

86/273 (31.5%)

Operative vaginal delivery

11/147 (7.5%)

26/273 (9.5%)

Breech vaginal delivery

0/147 (0.0%)

4/273 (1.5%)

Spontaneous vaginal delivery

71/147 (48.3%)

120/273 (44.0%)

Indication for delivery

Spontaneous

67/156 (43.0%)

106/282 (37.6%)

Routine

47/156 (30.1%)

104/282 (36.9%)

Fetal concerns

5/156 (3.2%)

7/282 (2.5%)

Worsening maternal cardiac disease

32/156 (20.5%)

38/282 (13.5%)

Pre-eclampsia

4/156 (2.6%)

12/282 (4.3%)

Other maternal disease

0/156 (0.0%)

2/282 (0.7%)

Unknown

1/156 (0.6%)

13/282 (4.6%)

EBL*

400 (50–4000)

400 (40–4000)

Multiple pregnancy

0/156 (0.0%)

2/282 (0.7%)

Perinatal outcomes

Birthweight centile*

25 (0–99)

24 (0–99)

Birthweight Z score

− 0.68 ± 1.18

− 0.71 ± 1.15

Birthweight centile < 10th

42/144 (29.2%)

86/269 (32.0%)

Birthweight centile < 3rd

21/144 (14.6%)

41/269 (15.2%)

NICU admission

28/106 (26.4%)

58/198 (29.3%)

Stillbirth

0/156 (0.0%)

0 (0.0%)

NND

1/156 (0.6%)

2/282 (0.7%)

Maternal outcomes

Pre-eclampsia

5/156 (3.2%)

13/282 (4.6%)

Severe pre-eclampsia

4/156 (2.6%)

9/282 (3.2%)

Early-onset pre-eclampsia (delivery < 34 weeks)

2/156 (1.3%)

5/282 (1.8%)

Preterm pre-eclampsia (delivery < 37 weeks)

3/156 (1.9%)

5/282 (1.8%)

Eclampsia

1/156 (0.6%)

1/282 (0.4%)

Gestation at pre-eclampsia diagnosis* (weeks + days)

33 + 0 (31 + 0 − 35 + 5)

33 + 0 (31 + 0 − 36 + 5)

Gestational diabetes

7/118 (5.9%)

13/221 (5.9%)

Placental abruption

2/119 (1.7%)

4/187 (2.1%)

PPROM

5/118 (2.5%)

10/221 (4.5%)

  1. Frequencies: n/N (%).
  2. *Median (range). Denominators vary between variables due to missing data.
  3. EBL Estimated blood loss, NICU Neonatal intensive care, NND Neonatal death, HELLP Haemolysis, elevated liver enzymes and low platelets; PPROM, premature rupture of membranes.