Figure 8
From: BHLHE40, a potential immune therapy target, regulated by FGD5-AS1/miR-15a-5p in pancreatic cancer
Abundant intercellular communication exists in classified immune cell subgroups with high BHLHE40 expression. (A) The umap plot demonstrates main cell types in PDAC. (B) Expression levels of BHLHE40 for all types of cells are plotted onto the umap. Color key from yellow to red indicates relative expression levels from low to high. The “expression level” was normalized by logNormalize method in Seurat. (C) Violin plots displaying the expression of BHLHE40 across the cell types identified in PDAC. The y axis shows the normalized read count. (D–M) The crosstalk between BHLHE40+ (Red)/BHLHE40− (Blue) clusters and other clusters. (N) The number of changes of crosstalk between BHLHE40+ cells and BHLHE40− cells.
