Figure 1
From: MALAT1 expression is associated with aggressive behavior in indolent B-cell neoplasms
MALAT1 expression levels in MBL, CLL#1 molecular subgroups, and RT. (a) MALAT1 expression was higher in CLL patients than in MBL (P < 0.001). Dotted line indicates the threshold of MALAT1 that determines differences in outcome. (b) No significant differences were observed in MALAT1 expression between CLL subgroups defined by IGHV mutational status (M-CLL versus U-CLL). (c) No significant differences were observed in MALAT1 expression between CLL subgroups defined by epigenetic subtypes (n-CLL: naïve-like, m-CLL: memory-like and i-CLL: intermediate) (right panel). (d) MALAT1 expression was higher in a series of 6 samples of CLL patients than in their corresponding paired RT samples (P < 0.01).
