Table 1 Patient characteristics.

From: Efficacy of chemotherapy for patients with gastric cancer with early recurrence during or after adjuvant chemotherapy with S-1 alone: a multicenter retrospective study

 

ALL (n = 207)

FP based (n = 91)

PTX based (n = 102)

IRI based (n = 14)

P-value

Age—median (range)

66 (42–84)

66 (42–84)

65 (42–83)

64 (57–77)

0.092

Sex

 Male

147 (71%)

69 (76%)

66 (64%)

10 (71%)

0.251

 Female

60 (29%)

22 (24%)

36 (36%)

4 (29%)

 

PS

 0/1

206 (99%)

91 (100%)

101 (99%)

14 (100%)

1.000

 2

1 (1%)

0

1 (1%)

0

 

HER2

 Positive

42 (20%)

30 (33%)

12 (12%)

0

0.001

 Negative

143 (69%)

55 (60%)

77 (75%)

11 (79%)

 

 Unknown

22 (11%)

6 (7%)

13 (13%)

3 (21%)

 

Histology

 Intestinal

81 (39%)

42 (46%)

33 (29%)

6 (43%)

0.138

 Diffuse

126 (61%)

49 (54%)

69 (71%)

8 (57%)

 

Metastasis site

 Peritoneum

84 (41%)

29 (32%)

51 (50%)

5 (36%)

0.032

Ascites

 Present

76 (37%)

26 (29%)

47 (46%)

3 (21%)

0.020

Number of metastatic sites

2

114 (55%)

55 (60%)

55 (54%)

4 (29%)

0.078

Time of recurrence

 During adjuvant S-1

125 (60%)

51 (56%)

65 (64%)

9 (64%)

0.533

 Within 6 months after adjuvant S-1

82 (40%)

40 (44%)

37 (36%)

5 (36%)

 
  1. Ordinal and categorical variables were compared using the Kruskal–Wallis test and Fisher’s exact test.
  2. HER2 Human epidermal growth factor receptor 2, PS performance status, FP fluoropyrimidines plus platinum based regimens, PTX paclitaxel based regimens, IRI irinotecan based regimens, ALL all patients.