Table 7 Summary of structural variations and antibacterial activity.

From: Synthesis and evaluation of vanillin Schiff bases as potential antimicrobial agents against ESBL-producing bacteria: towards novel interventions in antimicrobial stewardship

Compound

Key functional groups

MIC (μg/mL)

E. coli zone (mm)

K. pneumoniae zone (mm)

SB-1

Nitro, methoxy

125

16.0

14.4

SB-2

Bromo, methoxy

250

16.5

14.7

SB-3

Chloro, methyl, methoxy

125

14.8

15.0

SB-4

Hydroxy, methoxy

125

16.6

15.5

SB-5

Dichloro, methoxy

125

15.5

15.0

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