Fig. 7 | Scientific Reports

Fig. 7

From: Peroxiredoxin 6 maintains mitochondrial homeostasis and promotes tumor progression through ROS/JNK/p38 MAPK signaling pathway in multiple myeloma

Fig. 7The alternative text for this image may have been generated using AI.

Targeting PRDX6 restrains tumor growth in vivo. (A) Representative images of xenograft tumors from MM tumor-bearing mice in the control and knock down group. (B,C) Tumor weight and volume of xenograft tumors in the control and knock down group. (D) Representative images of xenograft tumors from MM tumor-bearing mice in the BTZ alone and combination group. (E,F) Tumor weight and volume of xenograft tumors in the BTZ alone and combination group. (F) H&E staining and IHC analysis of the protein levels of PRDX6, Ki67, Bcl2, Cleaved Caspase 3 and Cleaved PARP in tumor tissues from the control and deficiency mice bearing MM xenografts. Scale bar, 100 μm. The data are the mean ± SD. *p < 0.05, ns: no significance.

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