Fig. 6
From: rhaFGF promotes acute diabetic wound healing by suppressing chronicity of inflammation

Serological and wound tissue levels of IL-6 and TNF-α were assessed by ELISA in control and diabetic mice. Diabetic mice (DM) exhibited significantly higher serological (A) and wound tissue (B) IL-6 levels compared to controls. rhaFGF treatment (DM + rhaFGF) significantly reduced IL-6 levels in both serum and wound tissues. Similar to IL-6, serological (C) and wound tissue (D) levels of TNF-α levels were significantly elevated in DM compared to controls. rhaFGF treatment (DM + rhaFGF) significantly decreased TNF-α levels in both serum and wound tissues. *p < 0.05 and ****p < 0.0001.