Table 1 Comparison of the effects of D156844, AR42 and the combination of D156844 and AR42 (combo) treatments on the lifespan of SMNΔ7 SMA mice maintained on a PicoLab 20 diet. The D156844 data were previously published27.
Treatment | Mean lifespan ± SE (d) | Minimum lifespan (d) | Maximum lifespan (d) | Median lifespan ± SE (d) | Source |
|---|---|---|---|---|---|
D156844 | 17.7 ± 0.6 | 12.0 | 21.0 | 17.0 ± 0.6 | |
AR42 | 16.6 ± 0.7 | 13.0 | 22.0 | 16.0 ± 0.5 | this study |
AR42 + D156844 | 23.7 ± 3.5 | 12.0 | 65.0 | 21.0 ± 0.9 | this study |
vehicle | 13.9 ± 0.6 | 11.0 | 19.0 | 13.0 ± 0.8 | this study |
