Fig. 6 | Scientific Reports

Fig. 6

From: Development and validation of a visual nomogram for predicting clinically significant prostate cancer in negative mpMRI using 68Ga-PSMA PET/CT

Fig. 6The alternative text for this image may have been generated using AI.

Correction of misdiagnoses by PSP Model. Case 1. A 72-year-old man with PI-RADS score 2, SUVmax 10.5, PSA 8.4ng/ml, and PSAD 0.40ng/ml/cm3. (A) T2 showed homogeneous hyperplasia of the central and transition zones of the prostate; (B) DWI showed no significant diffusion restriction; (C) ADC signal was not reduced; (D) 68Ga-PSMA PET/CT showed a less obvious focal PSMA activity lesion (crosshair). The PSP Model indicated high risks (33.6% csPCa probability); biopsy pathology was ISUP 2 (Gleason 3+4). Case 2. A 69-year-old man with PI-RADS score 2, SUVmax 10.8, PSA 7.2ng/ml, and PSAD 0.18ng/ml/cm3. (E) T2 showed several well-circumscribed prostate nodules; (F-G) DWI showed slightly diffusion restriction, ADC signal was slightly reduced (green arrow); (H) 68Ga-PSMA PET/CT showed a less obvious focal PSMA activity lesion (crosshair). The PSP Model indicated low risks (27.0% csPCa probability); biopsy pathology were benign prostatic nodules. This figure is only an example case and is not directly representative of the overall statistical performance of the model.

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