Fig. 1

Levels of antibodies against Tat in PWH with more severe extrapyramidal motor abnormalities as measured by UPDRS scores of ≥ 10. The levels of plasma antibodies to gp120, Nef, p24, and Tat were examined in ELISA using a colorimetric substrate to yield optical density readings at 405 nm (OD₄₀₅). A Relative levels of plasma IgG antibodies against the four HIV antigens in PWH with varying UPDRS scores. The 42 PWH were grouped into four quartiles based on their UPDRS scores. p values from ANOVA are shown. B Relative IgG levels against the same four antigens in PWH with Global T-scores of ≥ 40 (normal) or < 40 (deficient). p values are from Mann-Whitney test.