Table 5 Molecular subtype by stage of the disease in the studied patients.

From: The clinicopathological and molecular landscape of breast cancer patients: a retrospective study in Sulaimaniyah, Iraq

Stage

No.

Molecular subtype

p-value

Luminal A

Luminal

B

Luminal B - HER2+

Low HER2 overexpression

High HER2 overexpression

Triple-negative

  

No. (%)

      

No lesion

13

1.0 (7.7)

0.0 (0.0)

8.0(61.5)

1.0 (7.7)

2.0 (15.4)

1.0 (7.7)

< 0.001*

I A

65

19 (29.2)

28 (43.1)

11 (16.9)

0.0 (0.0)

3.0 (4.6)

4.0 (6.2)

 

II A

91

22 (24.2)

38 (41.8)

18 (19.8)

0.0 (0.0)

1.0 (1.1)

12(13.2)

 

II B

52

17 (32.7)

17 (32.7)

13 (25.0)

0.0 (0.0)

1.0 (1.9)

4.0 (7.7)

 

III A

32

13 (40.6)

14 (43.7)

2.0 (6.3)

0.0 (0.0)

2.0 (6.3)

1.0 (3.1)

 

III C

47

9.0(19.1)

20 (42.6)

17 (36.2)

0.0 (0.0)

0.0 (0.0)

1.0 (2.1)

 

Total

300

81 (27.0)

117(39.0)

69 (23.0)

1.0 (0.3)

9.0 (3.0)

23 (7.7)

 
  1. *: Significant difference using Fisher’s exact test.