Fig. 3

(a, b) Volcano plot and heat map of differentially expressed genes between sample groups: (a) Volcano plot of differential genes. Each point in the figure represents a gene, green and red points represent significantly differentially expressed genes. The red dots indicate that the gene expression level is up-regulated, the green indicate down-regulated, and the black indicate that there is no significant difference between these genes; (b) Differential gene heat map. Each square in the heat map represents the relative expression of a gene in different samples. Red indicates high relative expression and blue indicates low; (c) The intersection and correlation analysis of m6A-FRGs related genes.