Fig. 4

(a) DE-COR-ME Venn. The blue circle represents DEGs, the yellow represents MEgenes, and the green represents the COR gene set; (b) GO enrichment results of differentially expressed genes: (b1) GO enrichment bar chart (the top 10 were screened and drawn according to significance ranking). The color represents p value. The redder the color, the smaller the value; (b2) GO enrichment chord diagram (top 16 were filtered for visualization based on significance ranking); (c) KEGG functional enrichment analysis; (d) PPI of m6A-FRGs-DEGs. Red nodes are up-regulated proteins, blue nodes are down-regulated, color depth and node size are distributed according to logFC, and the thickness of the connecting line is sorted according to the confidence of protein interaction; (e) Enrichment network analysis of m6A-FRGs-DEGs: (e1) The node colors represent different enriched pathway categories, the color ratio represents the number of genes overlapped by each pathway, and the thickness of the connecting line represents the degree of association between pathways; (e2) The bar graph corresponding to the enriched network. The length of the bar graph represents the number of enriched genes; (e3) The pie chart corresponding to the network diagram, the area of the pie chart represents the proportion of enriched pathway categories.