Table 5 Dosimetry comparison of clinical plan, autoplan, and RapidPlan.
From: Personalized intensity modulation radiation therapy auto-planning for esophageal cancer
Parameter | Clinical plan† (CP) | Autoplan* (AP) | RapidPlan* (RP) | p value | |||
|---|---|---|---|---|---|---|---|
CP vs AP | AP vs RP | CP vs RP | |||||
PTV | V100% | 95 ± 0.0 | 95 ± 0.0 | 95 ± 0.0 | -- | -- | -- |
Dmax[%] | 108.7 ± 2.2 | 108.6 ± 1.6 | 109.0 ± 1.6 | 0.630 | 0.008 | 0.094 | |
Lung | V5[%] | 45.2 ± 14.6 | 39.9 ± 13.4 | 41.2 ± 13.3 | <0.0001 | <0.0001 | <0.0001 |
V10 [%] | 30.3 ± 10.1 | 26.0 ± 9.6 | 27.5 ± 9.2 | <0.0001 | <0.0001 | <0.0001 | |
V20[%] | 16.0 ± 6.5 | 12.5 ± 6.0 | 13.0 ± 5.7 | <0.0001 | 0.001 | <0.0001 | |
Dmean[Gy] | 9.0 ± 2.9 | 8.0 ± 2.7 | 8.1 ± 2.6 | <0.0001 | 0.006 | <0.0001 | |
Spinal Cord | Dmax[Gy] | 35.6 ± 3.6 | 37.9 ± 1.2 | 35.7 ± 2.3 | <0.0001 | <0.0001 | <0.0001 |
Heart | V30 [%] | 36.3 ± 20.7 | 35.7 ± 18.9 | 31.8 ± 18.2 | 0.360 | <0.0001 | <0.0001 |
Dmean [Gy] | 22.1 ± 9.9 | 20.9 ± 9.2 | 20.3 ± 9.2 | <0.0001 | <0.0001 | <0.0001 | |
Liver | V30[%] | 3.7 ± 5.6 | 4.1 ± 6.0 | 4.2 ± 6.2 | <0.0001 | <0.0001 | <0.0001 |
Dmean[Gy] | 3.9 ± 4.4 | 3.8 ± 4.1 | 3.7 ± 4.3 | <0.0001 | <0.0001 | <0.0001 | |
Kidney_L | V20 [%] | 2.1 ± 5.3 | 2.0 ± 5.5 | 2.0 ± 7.8 | 0.980 | 0.220 | 0.160 |
Dmean[Gy] | 2.2 ± 3.3 | 2.2 ± 3.2 | 2.3 ± 3.8 | <0.0001 | 0.041 | 0.000 | |
Kidney_R | V20[%] | 0.5 ± 3.0 | 0.6 ± 2.2 | 0.5 ± 2.2 | 0.550 | 0.550 | 1.000 |
Dmean [Gy] | 1.3 ± 2.2 | 1.4 ± 1.9 | 1.4 ± 2.1 | <0.0001 | 0.069 | 0.000 | |
CI | 0.83 ± 0.06 | 0.84 ± 0.03 | 0.83 ± 0.04 | 0.913 | 0.006 | 0.021 | |
HI | 1.06 ± 0.02 | 1.07 ± 0.01 | 1.06 ± 0.01 | <0.0001 | <0.0001 | <0.0001 | |
MU | 851.5 ± 262.9 | 661.4 ± 131.7 | 701.3 ± 135.0 | <0.0001 | <0.0001 | <0.0001 | |
